Medycyna Wet. 57 (11), 836-839, 2001
| Samorek-Salamonowicz E., Czekaj H., Kozdruń W. |
| Immunomodulation of reproductive geese and maternal immunity against Derzsy’s disease in their offspring |
| The aim of this study was to determine the effect of Lydium-KLP and Levamisol administrated to goose layers after their vaccination against Derzsy’s disease on passive immunisation of goslings. Examinations were carried out in 3 reproduction flocks. During the vaccination geese in the flock A were given Lydium-KLP; in the flock B Levamisol was applied and birds in the control flock C received only a vaccine. These immunostimulators were administered again in the second half of the laying season. The presence of antibodies against Derzsy’s disease virus was determined by ELISA and seroneutralisation tests. High antibody levels was found in all 3 examined flocks at the beginning of the laying season in sera of goose layers, egg yolks and one-day-old goslings. Maternal antibodies were detected for 28 days at a level sufficient for the protection of goslings against Derzsy’s disease. Serological examinations carried out in the middle of laying season in geese and their offspring showed no statistical differences in antibody level among examined flocks. However, at the end of the laying season when serum antibody levels decreased, a similar decline was also observed in egg yolks and gosling sera. The application of Lydium-KLP and Levamisol caused longer maintenance and higher antibody levels in mothers. Thus immunostimulators caused better protection against Derzsy’s disease in progeny in comparison to birds which did not receive these preparations. Summing up, the application of immunostimulators in reproduction flocks during their vaccination against Derzsy’s disease did not have an influence on antibody levels during the first half of the laying season but showed favourable results at the end of the laying season. |
| Keywords: Lydium-KLP, Levamisol, maternal antibodies, seroneutralisation, ELISA |