Med. Weter. 81 (4), 151-158, 2025
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| YANLIN LI, DIANGANG HAN, YONG PENG, WEIDONG ZUO, BANGQUAN ZENG, DAI XIONG, JUN AI, JIGE XIN |
| Application of metagenomics in the animal infectious diseases |
| The increasing magnitude and density of livestock production on a global scale, the progressive degradation of biodiversity, and the phenomenon of global climate change have led to unparalleled diversification and intricacy in animal diseases. Precisely predicting epidemic trends, achieving early detection of outbreaks, and accurately identifying pathogens are imperative for developing precise control strategies and mitigating the risk of epidemic dissemination. Metagenomic next-generation sequencing (mNGS) has recently transitioned from an emerging technology to a crucial instrument for the early identification and prevention of emerging infectious diseases. It also facilitates the understanding of pathogen dissemination patterns and epidemiology and holds significant promise for advancements in infectious disease management. The objective of this review is to offer guidance and support for the implementation of mNGS in animal disease diagnosis and control by consolidating achievements, emphasizing the advantages and limitations of mNGS over conventional detection methods, and clarifying its present-day usage. |
| Keywords: Metagenomic sequencing, advantages and disadvantages, animal disease prevention and management |