Medycyna Wet. 65 (12), 857-861, 2009
| Barszcz K., Badurek I., Kleczkowski M., Kluciński W., Gajewski Z., Jakubowski T. |
| Effect of copper and magnesium on prooxidative-antioxidative status in the blood of cows in the transition period from deficient regions |
| The aim of the study was to evaluate the influence of copper and magnesium on superoxide dismutase (SOD) activity and concentration of malonyldialdehyde, ceruloplasmin, ascorbic acid, and total antioxidant status in the blood of cows from deficient regions. The research was conducted on a sample of 33 cows. The cows coming from deficient regions were divided into 3 groups: I (control), II and III (experimental) taking into account supplements. The mineral supplements were used as chemical compounds: copper for group II as Cu SO4.5 H2O, magnesium for group III as MgO. Samples of fodder were taken to determine copper and magnesium. Blood samples were taken from the jugular vein to estimate magnesium, copper, and superoxide dismutase activity and concentration of malonyldialdehyde, ceruloplasmin, ascorbic acid, and total antioxidant status. The concentration of copper and magnesium was lower in the blood of cows from the control group than that of the cows from the experimental groups. However, the concentration of malonyldialdehyde was higher in the control group than in the experimental groups. In the control group the superoxide dismutase activity, the concentration of ceruloplasmin and total antioxidant status were lower than in the experimental groups. Ascorbic acid concentration in the blood of cows from the control group was higher than in the experimental groups. The obtained data show that cooper and magnesium play an important role in many antioxidative mechanisms in the transition period of dairy cows. |
| Keywords: copper, magnesium, prooxidative-antioxidative status, cows |